Insulin signalling results in which of the following? Autophosphorylation of the G protein-coupled receptor which triggers a signalling cascade that stimulates the movement of GLUT4 towards the plasma membrane. Insulin signalling does not involve G proteins A decrease in the amount of fructose-6-phosphate converted to fructose-1,6-bisphosphate by L-phosphofructokinase-1. It activates a protein phosphatase which dephosphorylates glycogen phosphorylase to enhances the release of glucose from glycogen.
Question
Insulin signalling results in which of the following? Autophosphorylation of the G protein-coupled receptor which triggers a signalling cascade that stimulates the movement of GLUT4 towards the plasma membrane. Insulin signalling does not involve G proteins A decrease in the amount of fructose-6-phosphate converted to fructose-1,6-bisphosphate by L-phosphofructokinase-1. It activates a protein phosphatase which dephosphorylates glycogen phosphorylase to enhances the release of glucose from glycogen.
Solution
Insulin signaling results in the autophosphorylation of the insulin receptor, not a G protein-coupled receptor. This triggers a signaling cascade that stimulates the movement of GLUT4 towards the plasma membrane. This process allows cells, particularly muscle and fat cells, to take up glucose from the bloodstream.
The other options are incorrect:
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Insulin signaling does not decrease the amount of fructose-6-phosphate converted to fructose-1,6-bisphosphate by L-phosphofructokinase-1. Instead, insulin signaling promotes the conversion of glucose into glycogen for storage.
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Insulin signaling does not activate a protein phosphatase that dephosphorylates glycogen phosphorylase to enhance the release of glucose from glycogen. Instead, insulin signaling promotes the storage of glucose as glycogen. When insulin levels are low, glycogen phosphorylase is activated to break down glycogen and release glucose into the bloodstream.
Similar Questions
In the liver, insulin signalling down-regulates gluconeogenesis. Which of the following signalling pathways explains that mechanism?Group of answer choicesIt results in decreased expression of phosphoenolpyruvate carboxykinase.It results in the activation of cAMP dependent protein kinase A (PKA) which phosphorylates pyruvate kinase.It activates protein phosphatase-1 which dephosphorylates phosphofructokinase-2.It activates protein phosphatase-1 which dephosphorylates glycogen phosphorylase.
Au niveau du muscle, l'insulineAActive la translocation membranaire des transporteurs glut4BStimule la transcription de l'hexokinase 4CStimule la phosphorylation du glucoseDInhibe l'action de la glycogène phosphorylaseEStimule la phosphorylation de la glycogène synthase kinase
n muscle tissue, adrenaline signalling results inGroup of answer choicesDephosphorylation of the bifunctional PFK-2/FBPase-2 enzyme which increases glycolysis.Phosphorylation of glycogen phosphorylase which decreases glycogenolysis.Increased levels of fructose-1,6-bisphosphate production, which allosterically upregulates pyruvate kinase.The R state of phosphofructokinase-1 is not stabilised which decreases glycolysis.
L'insuline est une hormone clé dans la régulation du métabolisme des glucides, quelles sont les bonnes réponses 1. Elle active la glucokinase ; 2.Elle inhibe la PFK1; 3. Elle active la pyruvate carboxylase et inhibe la pyruvate déshydrogenase ; 4. Elle inhibe la pyruvate kinase ; 5. Elle inhibe la fructose 1,6 bi-phosphatase et active la phosphofructokinaca 1A1,2,4B2,3;C1,4,5D1,5;E1,3,5
La glycogénolyse est activée par : 1. Déphosphorylation de la glycogène phosphorylase; 2. Activation de la glycogène phosphorylase kinase 3. L'insuline; 4. Le glucagon; 5. Le glucose et l'ATPA1,3B4,5C2,4D1,4E2,5
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