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Older adults have a higher risk of adverse drug events compared with younger people because of higher blood levels.  Which of the following can lead to increased blood levels of medication with aging?Group of answer choicesKidney function declinesAbsorption of medication is increased through the stomachLiver enzymes are more activeAll of the above

Question

Older adults have a higher risk of adverse drug events compared with younger people because of higher blood levels.  Which of the following can lead to increased blood levels of medication with aging?Group of answer choicesKidney function declinesAbsorption of medication is increased through the stomachLiver enzymes are more activeAll of the above

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Solution

The correct answer is "Kidney function declines".

As people age, their kidney function often declines. This means the kidneys are less able to filter out waste products, including medications, from the blood. As a result, the levels of medication in the blood can increase, leading to a higher risk of adverse drug events.

While absorption of medication through the stomach can change with age, it does not necessarily increase. In fact, it can often decrease due to changes in stomach acidity and other factors.

Liver enzymes do not typically become more active with age. In fact, liver function can also decline, which can affect the metabolism of medications. However, this would not directly lead to increased blood levels of medication.

Therefore, out of the options provided, only the decline in kidney function can lead to increased blood levels of medication with aging.

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