What energy is released when the chemical bonds of glucose are broken?
Question
What energy is released when the chemical bonds of glucose are broken?
Solution
To determine the energy released when the chemical bonds of glucose are broken, follow these steps:
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Identify the chemical formula of glucose: The molecular formula of glucose is C6H12O6.
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Understand the process of glucose breakdown: The primary process for breaking down glucose in cells is cellular respiration, which includes glycolysis, the citric acid cycle (Krebs cycle), and oxidative phosphorylation.
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Calculate the energy yield from glycolysis:
- Glycolysis occurs in the cytoplasm and converts one molecule of glucose into two molecules of pyruvate.
- This process produces a net gain of 2 ATP (adenosine triphosphate) molecules and 2 NADH (nicotinamide adenine dinucleotide) molecules.
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Calculate the energy yield from the citric acid cycle:
- Each pyruvate molecule enters the mitochondria and is converted into acetyl-CoA, which then enters the citric acid cycle.
- For each glucose molecule, the citric acid cycle produces 2 ATP, 6 NADH, and 2 FADH2 (flavin adenine dinucleotide) molecules.
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Calculate the energy yield from oxidative phosphorylation:
- NADH and FADH2 produced in glycolysis and the citric acid cycle donate electrons to the electron transport chain in the inner mitochondrial membrane.
- Each NADH can produce approximately 2.5 ATP, and each FADH2 can produce approximately 1.5 ATP through oxidative phosphorylation.
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Sum the total ATP produced:
- From glycolysis: 2 ATP + (2 NADH * 2.5 ATP/NADH) = 2 ATP + 5 ATP = 7 ATP
- From the citric acid cycle: 2 ATP + (6 NADH * 2.5 ATP/NADH) + (2 FADH2 * 1.5 ATP/FADH2) = 2 ATP + 15 ATP + 3 ATP = 20 ATP
- Total ATP from one glucose molecule: 7 ATP (glycolysis) + 20 ATP (citric acid cycle) = 27 ATP
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Consider the ATP yield from pyruvate conversion:
- Each pyruvate conversion to acetyl-CoA produces 1 NADH, and since there are 2 pyruvate molecules per glucose, this adds 2 NADH.
- 2 NADH * 2.5 ATP/NADH = 5 ATP
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Add the ATP from pyruvate conversion:
- Total ATP from one glucose molecule: 27 ATP + 5 ATP = 32 ATP
Therefore, the energy released when the chemical bonds of one molecule of glucose are broken down through cellular respiration is approximately 32 ATP molecules.
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