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When are chromosomes visible?

Question

When are chromosomes visible?

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Solution

Chromosomes become visible during the metaphase stage of cell division, specifically during mitosis and meiosis. Here are the steps:

  1. Interphase: This is the phase where the cell prepares for division by replicating its DNA. However, chromosomes are not visible under a light microscope because they are in a relaxed state known as chromatin.

  2. Prophase: This is the first stage of cell division. The chromatin condenses and starts to become visible as chromosomes. The nuclear envelope begins to break down.

  3. Metaphase: This is the stage when chromosomes become fully visible under a light microscope. They align at the metaphase plate (the equatorial plane of the cell). Each chromosome is composed of two sister chromatids attached at a point called the centromere.

  4. Anaphase: The sister chromatids separate and move towards opposite poles of the cell. They are still visible as individual chromosomes.

  5. Telophase: The chromosomes reach the poles and begin to decondense back into chromatin. A new nuclear envelope forms around each set of chromosomes.

  6. Cytokinesis: The cell splits into two daughter cells. The chromosomes are no longer visible as they have returned to the chromatin state.

So, in summary, chromosomes are most visible during the metaphase stage of cell division.

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