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A 36-year-old man presents with the following blood biochemistry results:Analyte (SERUM)ResultReference intervalSodium146135 – 145 mmol/LPotassium6.83.5 – 5.5 mmol/LChloride10895 – 110 mmol/LBicarbonate2222 – 32 mmol/LUrea36.63.0 – 8.0 mmol/LCreatinine37740 – 90 μmol/LeGFR50> 90 ml/min/1.73m2Considering the abnormal results, what is the likely diagnosis for this patient?Group of answer choicesHe has acute kidney diseaseHe is on thiazide diureticsHe has metabolic acidosisHe has chronic diarrhea

Question

A 36-year-old man presents with the following blood biochemistry results:Analyte (SERUM)ResultReference intervalSodium146135 – 145 mmol/LPotassium6.83.5 – 5.5 mmol/LChloride10895 – 110 mmol/LBicarbonate2222 – 32 mmol/LUrea36.63.0 – 8.0 mmol/LCreatinine37740 – 90 μmol/LeGFR50> 90 ml/min/1.73m2Considering the abnormal results, what is the likely diagnosis for this patient?Group of answer choicesHe has acute kidney diseaseHe is on thiazide diureticsHe has metabolic acidosisHe has chronic diarrhea

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Solution

The patient's blood biochemistry results show elevated levels of Sodium, Potassium, Urea, and Creatinine, along with a decreased eGFR (estimated Glomerular Filtration Rate). These results suggest impaired kidney function, as the kidneys are responsible for filtering out these substances from the blood.

The elevated Sodium (Hypernatremia) and Potassium (Hyperkalemia) levels indicate that the kidneys are not effectively filtering these electrolytes.

The increased Urea and Creatinine levels are also indicative of reduced kidney function. Urea and Creatinine are waste products that the kidneys filter out of the blood. When their levels are high, it suggests that the kidneys are not effectively removing these waste products.

The decreased eGFR further supports the diagnosis of kidney disease. The eGFR is a measure of how well the kidneys are filtering waste from the blood. A normal eGFR is over 90 ml/min/1.73m2. This patient's eGFR is significantly lower than the normal range, indicating reduced kidney function.

Therefore, based on these abnormal results, the likely diagnosis for this patient is acute kidney disease.

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