What are the facts about the use of bacteriostatic agents in WF used for parenteral products?Select all that apply. A. The addition of a bacteriostat may provide some protection from contamination of a multi-dose vial if the product is contaminated after the vial is opened and the first dose has been extracted. B. The names and proportions of antimicrobial agents used in Bacteriostatic WFI must be stated on the label. C. Bacteriostatic WFI may be used for rehydrating small volume injectables, not more than 30 ml in a vial. D. Bacteriostatic WFI is used in neonatal medicine because tiny babies are so susceptible to infection from contaminated products.
Question
What are the facts about the use of bacteriostatic agents in WF used for parenteral products?Select all that apply. A. The addition of a bacteriostat may provide some protection from contamination of a multi-dose vial if the product is contaminated after the vial is opened and the first dose has been extracted. B. The names and proportions of antimicrobial agents used in Bacteriostatic WFI must be stated on the label. C. Bacteriostatic WFI may be used for rehydrating small volume injectables, not more than 30 ml in a vial. D. Bacteriostatic WFI is used in neonatal medicine because tiny babies are so susceptible to infection from contaminated products.
Solution
A. True. The addition of a bacteriostat can indeed provide some protection from contamination of a multi-dose vial if the product is contaminated after the vial is opened and the first dose has been extracted.
B. True. The names and proportions of antimicrobial agents used in Bacteriostatic Water for Injection (WFI) must be stated on the label. This is to ensure transparency and safety in its usage.
C. True. Bacteriostatic WFI can be used for rehydrating small volume injectables, not more than 30 ml in a vial. This is because the bacteriostatic agents in the water can prevent the growth of bacteria in these small volumes.
D. False. Bacteriostatic WFI is not typically used in neonatal medicine. This is because the bacteriostatic agents in the water can have adverse effects on neonates. Instead, sterile water for injection, which does not contain any bacteriostatic agents, is typically used.
Similar Questions
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