If glucose is broken down through aerobic respiration, a number of ATP molecules can be made from the energy extracted. How many molecules of ATP are possible?A. 10 to 12B. 2 to 4C. 36 to 38D. 24 to 30
Question
If glucose is broken down through aerobic respiration, a number of ATP molecules can be made from the energy extracted. How many molecules of ATP are possible?A. 10 to 12B. 2 to 4C. 36 to 38D. 24 to 30
Solution 1
To determine the number of ATP molecules that can be produced through aerobic respiration, we need to consider the process of glycolysis, the Krebs cycle, and the electron transport chain.
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Glycolysis: In the cytoplasm, glucose is broken down into two molecules of pyruvate. During this process, a net gain of 2 ATP molecules is produced.
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Krebs cycle: Each pyruvate molecule enters the mitochondria and is converted into acetyl-CoA. In the Krebs cycle, acetyl-CoA is further broken down, releasing energy. For each acetyl-CoA molecule, 3 NADH, 1 FADH2, and 1 ATP molecule are produced. Since two molecules of pyruvate are generated from one glucose molecule, the total yield from the Krebs cycle is 6 NADH, 2 FADH2, and 2 ATP molecules.
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Electron transport chain: The NADH and FADH2 molecules produced in the previous steps enter the electron transport chain, located in the inner mitochondrial membrane. Through a series of redox reactions, these molecules donate electrons, which generate a proton gradient across the membrane. This gradient drives ATP synthesis. Each NADH molecule can produce approximately 2.5 ATP molecules, while each FADH2 molecule can produce approximately 1.5 ATP molecules.
Considering the above steps, we can calculate the total ATP yield from one molecule of glucose:
Glycolysis: 2 ATP Krebs cycle: 2 ATP NADH from Krebs cycle: 6 NADH x 2.5 ATP = 15 ATP FADH2 from Krebs cycle: 2 FADH2 x 1.5 ATP = 3 ATP
Total ATP yield = 2 + 2 + 15 + 3 = 22 ATP
Therefore, the correct answer is D. 24 to 30 ATP.
Solution 2
To determine the number of ATP molecules that can be produced through aerobic respiration, we need to consider the process of glycolysis, the Krebs cycle, and the electron transport chain.
-
Glycolysis: In the cytoplasm, glucose is broken down into two molecules of pyruvate. During this process, a net gain of 2 ATP molecules is produced.
-
Krebs cycle: Each pyruvate molecule enters the mitochondria and is converted into acetyl-CoA. In the Krebs cycle, acetyl-CoA is further broken down, releasing energy. For each acetyl-CoA molecule, 3 NADH, 1 FADH2, and 1 ATP molecule are produced. Since two molecules of pyruvate are generated from one glucose molecule, the total yield from the Krebs cycle is 6 NADH, 2 FADH2, and 2 ATP molecules.
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Electron transport chain: The NADH and FADH2 molecules produced in the previous steps enter the electron transport chain, located in the inner mitochondrial membrane. Through a series of redox reactions, these molecules donate electrons, which generate a proton gradient across the membrane. This gradient drives ATP synthesis. Each NADH molecule can produce approximately 2.5 ATP molecules, while each FADH2 molecule can produce approximately 1.5 ATP molecules.
Considering the above steps, we can calculate the total ATP yield from one molecule of glucose:
Glycolysis: 2 ATP Krebs cycle: 2 ATP NADH from Krebs cycle: 6 NADH x 2.5 ATP = 15 ATP FADH2 from Krebs cycle: 2 FADH2 x 1.5 ATP = 3 ATP
Total ATP yield = 2 + 2 + 15 + 3 = 22 ATP
Therefore, the correct answer is D. 24 to 30 ATP.
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