After arrival of antigen in lymphoid tissue and the activation of resident B cells, which of the following processes does NOT occur in the lymphoid follicles?Select one alternative:Isotype switching of B cells to change the Fc region of the antibody that will be produced.Affinity maturation of the B cells to produce antibody of the highest affinity for the antigen.Migration of B cells into T cell rich areas of the follicle to receive T cell help.Clonal proliferation to produce an "army" of identical B cells with the same antigen-binding specificity.
Question
After arrival of antigen in lymphoid tissue and the activation of resident B cells, which of the following processes does NOT occur in the lymphoid follicles?Select one alternative:Isotype switching of B cells to change the Fc region of the antibody that will be produced.Affinity maturation of the B cells to produce antibody of the highest affinity for the antigen.Migration of B cells into T cell rich areas of the follicle to receive T cell help.Clonal proliferation to produce an "army" of identical B cells with the same antigen-binding specificity.
Solution 1
Migration of B cells into T cell rich areas of the follicle to receive T cell help. This process does not occur in the lymphoid follicles. Instead, it occurs in the germinal centers of the lymph nodes.
Solution 2
The process that does NOT occur in the lymphoid follicles after the arrival of antigen and the activation of resident B cells is: Migration of B cells into T cell rich areas of the follicle to receive T cell help.
This process actually occurs before the B cells move into the lymphoid follicles. The B cells first interact with T cells in the T cell-rich areas of the lymph node (also known as the paracortex), where they receive signals that help them to differentiate and proliferate. After this interaction, the B cells move into the follicles where they undergo processes like isotype switching and affinity maturation.
Similar Questions
Which of the following is a common feature between T and B cells?ANSWERBoth will undergo proliferation and differentiation to make plasma cells.Both mature in the bone marrow.Both require an antigen-presenting cell to become activated.Both produce memory cells after activation.
Duringaffinity maturation, B-cells will undergo somatic hypermutation in the ______zone and selection for improved CDR binding in the _______ zone. After theseprocesses the TH cell may direct the B cell to leave and head to thesite of an infection and secrete antibodies there, which will cause the B cellto _________.
T and B cells undergo the development and maturation process in ______.
Whichof the following processes in the differentiation of the B-cell lineage takesplace primarily in the bone marrow (as opposed to the lymph nodes)?1 point removalof the gene regions coding for the mand δ heavy chain constant domains mutationdirected to the variable domain regions specifying the structures of the CDRloops negativeselection to remove B cells that recognize self-antigen activationof B cells by foreign antigen rearrangementof the genes that code for T-cell receptors
Which lymphocyte moves to the thymus gland to mature? A. B cells B. T cells C. NK cells D. None
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.