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Which of the following neurological diseases is paired with the correct aetiology/pathogenesis/consequences?Question 22Select one:a.Progressive Bulbar Palsy (PBP) – intellectual disabilityb.Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).c.Alzheimer's Disease – .Presence of Lewy bodies and reduced dopamine productiond.Epilepsy - Increased frequency or number of action potentialse.Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotonia

Question

Which of the following neurological diseases is paired with the correct aetiology/pathogenesis/consequences?Question 22Select one:a.Progressive Bulbar Palsy (PBP) – intellectual disabilityb.Parkinson's Disease – neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).c.Alzheimer's Disease – .Presence of Lewy bodies and reduced dopamine productiond.Epilepsy - Increased frequency or number of action potentialse.Spastic Cerebral Palsy - Involuntary, jerky movements and muscle hypotonia

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Solution

The correct pairing is d. Epilepsy - Increased frequency or number of action potentials.

Here's why:

a. Progressive Bulbar Palsy (PBP) – This is a type of motor neuron disease, not typically associated with intellectual disability.

b. Parkinson's Disease – This disease is characterized by the death of dopamine-generating cells in the substantia nigra, a region of the midbrain, not by neurofibrillary tangles and atrophy of neurons at the surface of the brain (cortex).

c. Alzheimer's Disease – This disease is characterized by the formation of amyloid plaques and neurofibrillary tangles, not the presence of Lewy bodies and reduced dopamine production.

d. Epilepsy - This is correctly paired. Epilepsy is a neurological disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of awareness. This can be due to an increased frequency or number of action potentials.

e. Spastic Cerebral Palsy - This condition is characterized by increased muscle tone resulting in stiffness and involuntary movements, not involuntary, jerky movements and muscle hypotonia (which is low muscle tone).

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