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How many molecules of NADPH are required for 12 molecules of RuBP to be carboxylated by rubisco?

Question

How many molecules of NADPH are required for 12 molecules of RuBP to be carboxylated by rubisco?

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Solution

The process of carboxylation of RuBP (Ribulose-1,5-bisphosphate) by the enzyme Rubisco (Ribulose-1,5-bisphosphate carboxylase/oxygenase) is the first major step of the Calvin cycle in photosynthesis.

In this process, each molecule of RuBP is carboxylated to form two molecules of 3-phosphoglycerate (3-PGA). This reaction does not directly involve NADPH.

However, in the subsequent steps of the Calvin cycle, these 3-PGA molecules are reduced to glyceraldehyde-3-phosphate (G3P) in a process that requires NADPH. Specifically, each 3-PGA molecule requires 1 molecule of NADPH for its reduction.

So, for each RuBP molecule that is carboxylated, 2 molecules of NADPH are required (because each RuBP produces 2 molecules of 3-PGA).

Therefore, for 12 molecules of RuBP to be carboxylated, 12 * 2 = 24 molecules of NADPH would be required.

This problem has been solved

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