Which one of the following statements is INCORRECT? Question 5Select one:a.During exercise or fasting, inhibition of the pyruvate dehydrogenase enzyme allows us to burn fat while preserving our limited carbohydrate reserves.b.Insulin can inhibit ketogenesis by inhibiting the carnitine carrier protein located on the mitochondrial membrane.c.In adipocytes, insulin signalling allows excess acetyl CoA to leave the mitochondria to enter the lipogenesis pathwayd.The enzyme glucose-6-phosphatase (G6Pase) in skeletal muscle cells allows the cell to produce glucose for export into the bloodstream during hypoglycaemia.e.Insulin promotes the insertion of the GLUT4 transporter protein into the cell membrane through the phosphatidylinositol (PI) pathway.
Question
Which one of the following statements is INCORRECT? Question 5Select one:a.During exercise or fasting, inhibition of the pyruvate dehydrogenase enzyme allows us to burn fat while preserving our limited carbohydrate reserves.b.Insulin can inhibit ketogenesis by inhibiting the carnitine carrier protein located on the mitochondrial membrane.c.In adipocytes, insulin signalling allows excess acetyl CoA to leave the mitochondria to enter the lipogenesis pathwayd.The enzyme glucose-6-phosphatase (G6Pase) in skeletal muscle cells allows the cell to produce glucose for export into the bloodstream during hypoglycaemia.e.Insulin promotes the insertion of the GLUT4 transporter protein into the cell membrane through the phosphatidylinositol (PI) pathway.
Solution
The incorrect statement is:
d. The enzyme glucose-6-phosphatase (G6Pase) in skeletal muscle cells allows the cell to produce glucose for export into the bloodstream during hypoglycaemia.
Explanation:
Glucose-6-phosphatase is an enzyme that is present in the liver and kidney but not in muscle. This enzyme is responsible for the final step in gluconeogenesis and glycogenolysis, where it catalyzes the dephosphorylation of glucose-6-phosphate to glucose. Muscle lacks this enzyme, so it cannot export glucose into the bloodstream. Instead, glucose-6-phosphate in muscle is used internally for glycolysis or stored as glycogen.
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