In nucleophilic acyl substitution, which is the worst leaving group?Select answer from the options belowH3C-Cl-H2N-RO-
Question
In nucleophilic acyl substitution, which is the worst leaving group?Select answer from the options belowH3C-Cl-H2N-RO-
Solution
In nucleophilic acyl substitution, the worst leaving group would be H2N-. This is because amine groups (H2N-) are strong bases and poor leaving groups. They are less likely to accept a pair of electrons, making them less likely to leave during the reaction.
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