Why does water stop a Grignard reaction?Select answer from the options belowWater will freeze during Grignard conditionsWater deprotonates the Grignard reagentWater protonates the Grignard reagentWater complexes the magnesium and slows its reactivity
Question
Why does water stop a Grignard reaction?Select answer from the options belowWater will freeze during Grignard conditionsWater deprotonates the Grignard reagentWater protonates the Grignard reagentWater complexes the magnesium and slows its reactivity
Solution
Water protonates the Grignard reagent.
Here's why: Grignard reagents are extremely basic and will react with any source of protons, including water. When a Grignard reagent comes into contact with water, it will immediately grab a proton (H+) from the water molecule, thus neutralizing the Grignard reagent and stopping the reaction. This is why Grignard reactions must be carried out in anhydrous (water-free) conditions.
Similar Questions
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