The hemoglobin-oxygen (Hb-O2) dissociation curve at high altitude (red) has a distinct shape from that at atmospheric pressure (black). Which of the following best explains the sigmoidal shape of the curves?  A.Dissolved oxygen in the blood serves to increase pH.B.The primary structure of Hb is changed by oxygen binding.C.Dissolved oxygen forms a chain of atoms that binds more easily to Hb.D.Homotropic regulation by oxygen occurs.

On ascent to high altitude, there is a marked drop in Hb-O2 saturation, this drop can be explained by: (Select all that are correct. There may be one or more correct options)Group of answer choicesFall in temperature in the atmosphere creates a right ward shift of the Hb-O2 curveDecrease barometric air pressure means the air is less dense and thus the number of O2 molecules inspired with each breath is lessDecrease barometric air pressure decrease O2 partial pressure in the surrounding airPercentage composition of oxygen decreases with altitude, thus less O2 is inspired with each breath

Which statement is true about the Oxygen - hemoglobin dissociation curve:Question 21Answera.Hemoglobin is likely to be fully saturated near resting cells/tissuesb.Hemoglobin is likely to be fully saturated near exercising cells/tissuesc.The curve would shift to the left when arterial CO2 is highd.The curve would shift to the right when body temperature decreasese.Hemoglobin stays nearly fully saturated at ≥70mmHg of PO2Clear my choice

Which of the following does not shift the oxy-haemoglobin dissociation curve to the right?1. increased pH2. increased carbon dioxide3. increased temperature4. increased 2,3 -DPG

explain/understand how hemoglobin binds oxygen

hyperbolic binding curve differs from a sigmoidal binding curve in that the hyperbolic curveAnswers: A. has a single constant affinity for oxygen binding.B. binds more oxygen after the initial proteins first bind oxygen.C. shows cooperativity.D. binds up to four molecules of oxygen.E. All of the above