9) Which of the following is true?a) Peripheral chemoreceptors increase firing with low arterial PO2 but are notsensitive to an increase in arterial PCO2.b) The primary stimulus to the central chemoreceptors is low arterial PO2.c) Peripheral chemoreceptors increase firing during a metabolic alkalosis.d) The increase in ventilation during exercise is due to a decrease in arterial PO2.e) Peripheral and central chemoreceptors both increase firing when arterial PCO2increases.
Question
- Which of the following is true?a) Peripheral chemoreceptors increase firing with low arterial PO2 but are notsensitive to an increase in arterial PCO2.b) The primary stimulus to the central chemoreceptors is low arterial PO2.c) Peripheral chemoreceptors increase firing during a metabolic alkalosis.d) The increase in ventilation during exercise is due to a decrease in arterial PO2.e) Peripheral and central chemoreceptors both increase firing when arterial PCO2increases.
Solution
The correct answer is e) Peripheral and central chemoreceptors both increase firing when arterial PCO2 increases.
Here's why:
a) Peripheral chemoreceptors are sensitive to both low arterial PO2 and high arterial PCO2, so this statement is false.
b) The primary stimulus to the central chemoreceptors is high arterial PCO2, not low arterial PO2, so this statement is false.
c) Peripheral chemoreceptors actually decrease firing during a metabolic alkalosis, so this statement is false.
d) The increase in ventilation during exercise is primarily due to an increase in CO2 production and not a decrease in arterial PO2, so this statement is false.
e) Both peripheral and central chemoreceptors increase firing when arterial PCO2 increases. This is because an increase in arterial PCO2 indicates a rise in blood acidity, which these chemoreceptors respond to by increasing their firing rate to stimulate an increase in ventilation and thus reduce the PCO2 levels. Therefore, this statement is true.
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