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Glycogen Metabolism occurs in the__________*1 pointHeartCells in all parts of the bodyLiverKidney

Question

Glycogen Metabolism occurs in the__________*1 pointHeartCells in all parts of the bodyLiverKidney

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Solution

Glycogen metabolism occurs primarily in the liver and muscles.

Here are the steps:

  1. Glycogen metabolism involves the breakdown (glycogenolysis) and synthesis (glycogenesis) of glycogen.

  2. Glycogen is a multi-branched polysaccharide of glucose that serves as a form of energy storage in animals

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The pentose phosphate pathway occurs in the__________*1 pointLiverKidneyHeartCells in all parts of the body

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Glycogen molecules are stored in liver and --------------

The body's largest stores of glycogen are found in the liver and skeletal muscles.  Individual glucosyl residues (ie, glucose monomers) in muscle and liver glycogen particles are linked by α(1→4) and α(1→6) glycosidic bonds and are released in the reactions of glycogenolysis.  Glycogen phosphorylase catalyzes the removal of most of the glucosyl residues, although debranching enzyme also releases the single glucose molecule that remains after it repositions three residues onto an adjacent linear chain.Binding of the hormone epinephrine to its receptor on the surface of muscle cells stimulates muscle glycogenolysis through activation of a signaling cascade (Figure 1).Figure 1  Stimulation of skeletal muscle glycogenolysis by epinephrine.The relative signal amplification (SA) at each step (I–IV in Figure 1) can be determined by comparing the number of active signaling molecules before (Mbefore) and after (Mafter) the step:SA=MafterMbeforeSA=𝑀after𝑀before Question 36The skeletal muscles collectively contain more than twice as much glucose stored in glycogen as is found in the liver.  Compared with the liver, the amount of glucose released into the blood from muscles is likely:A.greater from glycogenolysis, but less from gluconeogenesis.B.the same from glycogenolysis, but more from gluconeogenesis.C.less from both glycogenolysis and gluconeogenesis.D.the same from both glycogenolysis and gluconeogenesis.

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