The glucose transport channel of GLUT1 is a transmembrane protein, which means it spans the entire membrane and is exposed to both the inside and outside of the cell. Transmembrane proteins often have hydrophobic (water-repelling) regions that interact with the hydrophobic interior of the lipid bilayer.

Amino acids can be classified as hydrophobic, hydrophilic, or charged. Hydrophobic amino acids are nonpolar and prefer to be in a non-aqueous environment, such as the lipid bilayer of a cell membrane. Hydrophilic amino acids are polar and prefer to be in an aqueous environment, such as the cytoplasm or extracellular fluid. Charged amino acids can be either positively or negatively charged and also prefer to be in an aqueous environment.

Looking at the peptide sequences:

1. RLVTEFIELVKILVRLVDIVL: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (T, E), and charged (R) amino acids.

2. LERVKRELRKLERKIEEVKED: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (E), and charged (R, K, D) amino acids.

3. SLVTNFISLVTNLVSLVTIVL: This sequence contains a mix of hydrophobic (V, I, L, F), hydrophilic (S, T, N), and no charged amino acids.

4. LSTVSNTLSTLSNTISSVTSN: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (S, T, N), and no charged amino acids.

The peptide sequence that would best fulfill the role of one of the transmembrane helices lining the glucose transport channel of GLUT1 would be the one with the most hydrophobic amino acids and the least hydrophilic and charged amino acids.

Therefore, the best choice would be "SLVTNFISLVTNLVSLVTIVL" as it contains the most hydrophobic amino acids (V, I, L, F) and the least hydrophilic (S, T, N) and no charged amino acids. This would allow it to interact best with the hydrophobic interior of the lipid bilayer.

Question

The glucose transport channel of GLUT1 is a transmembrane protein, which means it spans the entire membrane and is exposed to both the inside and outside of the cell. Transmembrane proteins often have hydrophobic (water-repelling) regions that interact with the hydrophobic interior of the lipid bilayer.

Amino acids can be classified as hydrophobic, hydrophilic, or charged. Hydrophobic amino acids are nonpolar and prefer to be in a non-aqueous environment, such as the lipid bilayer of a cell membrane. Hydrophilic amino acids are polar and prefer to be in an aqueous environment, such as the cytoplasm or extracellular fluid. Charged amino acids can be either positively or negatively charged and also prefer to be in an aqueous environment.

Looking at the peptide sequences:

1. RLVTEFIELVKILVRLVDIVL: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (T, E), and charged (R) amino acids.

2. LERVKRELRKLERKIEEVKED: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (E), and charged (R, K, D) amino acids.

3. SLVTNFISLVTNLVSLVTIVL: This sequence contains a mix of hydrophobic (V, I, L, F), hydrophilic (S, T, N), and no charged amino acids.

4. LSTVSNTLSTLSNTISSVTSN: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (S, T, N), and no charged amino acids.

The peptide sequence that would best fulfill the role of one of the transmembrane helices lining the glucose transport channel of GLUT1 would be the one with the most hydrophobic amino acids and the least hydrophilic and charged amino acids.

Therefore, the best choice would be "SLVTNFISLVTNLVSLVTIVL" as it contains the most hydrophobic amino acids (V, I, L, F) and the least hydrophilic (S, T, N) and no charged amino acids. This would allow it to interact best with the hydrophobic interior of the lipid bilayer.

Knowee AI · Accepted Answer

The glucose transport channel of GLUT1 is a transmembrane protein, which means it spans the entire membrane and is exposed to both the inside and outside of the cell. Transmembrane proteins often have hydrophobic (water-repelling) regions that interact with the hydrophobic interior of the lipid bilayer.

Amino acids can be classified as hydrophobic, hydrophilic, or charged. Hydrophobic amino acids are nonpolar and prefer to be in a non-aqueous environment, such as the lipid bilayer of a cell membrane. Hydrophilic amino acids are polar and prefer to be in an aqueous environment, such as the cytoplasm or extracellular fluid. Charged amino acids can be either positively or negatively charged and also prefer to be in an aqueous environment.

Looking at the peptide sequences:

1. RLVTEFIELVKILVRLVDIVL: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (T, E), and charged (R) amino acids.

2. LERVKRELRKLERKIEEVKED: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (E), and charged (R, K, D) amino acids.

3. SLVTNFISLVTNLVSLVTIVL: This sequence contains a mix of hydrophobic (V, I, L, F), hydrophilic (S, T, N), and no charged amino acids.

4. LSTVSNTLSTLSNTISSVTSN: This sequence contains a mix of hydrophobic (V, I, L), hydrophilic (S, T, N), and no charged amino acids.

The peptide sequence that would best fulfill the role of one of the transmembrane helices lining the glucose transport channel of GLUT1 would be the one with the most hydrophobic amino acids and the least hydrophilic and charged amino acids.

Therefore, the best choice would be "SLVTNFISLVTNLVSLVTIVL" as it contains the most hydrophobic amino acids (V, I, L, F) and the least hydrophilic (S, T, N) and no charged amino acids. This would allow it to interact best with the hydrophobic interior of the lipid bilayer.

Which of the following peptide sequences would best fulfil the role of one of the transmembrane helices lining the glucose transport channel of GLUT1? Group of answer choices RLVTEFIELVKILVRLVDIVL LERVKRELRKLERKIEEVKED SLVTNFISLVTNLVSLVTIVL LSTVSNTLSTLSNTISSVTSN

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