The water-soluble vitamin deficiency that may eventually lead to megaloblastic anemia is due to a lack of which vitamin?Multiple choice question.ironthiaminbiotinfolate
Question
The water-soluble vitamin deficiency that may eventually lead to megaloblastic anemia is due to a lack of which vitamin?Multiple choice question.ironthiaminbiotinfolate
Solution
The water-soluble vitamin deficiency that may eventually lead to megaloblastic anemia is due to a lack of folate.
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Globally, an estimated two billion individuals are impacted by a persistent deficiency of essential vitamins and minerals (micronutrients). The most common micronutrient deficiencies include iron, vitamin B12, vitamin D, zinc, and vitamin B2 (Allen, Peerson, & Olney, 2009). The first two of these deficiencies are associated with one of the most common diseases, anemia.Anemia is caused by a deficiency of red blood cells or hemoglobin, where the body is unable to produce an adequate number of healthy red blood cells. Hemoglobin is a protein molecule within red blood cells that carries oxygen to tissue throughout the body (Guo, Zhou, Jia, & Xu, 2019). Because hemoglobin transports oxygen from the lungs to the capillaries, anemia leads to hypoxia. Symptoms may be related to an underlying cause or to the anemia itself. Anemia is associated with symptoms including weakness, shortness of breath, and serious health risks including abnormal mental and motor development (Harrabi et al., 2021). Elements contributing to the formation and development of red blood cells and hemoglobin synthesis include iron, as well as other minerals such as copper, zinc, magnesium, cobalt, and molybdenum, vitamins (particularly folic acid and vitamin B12), and amino acids. Several factors, including food insufficiency, and certain customs and habits, can contribute to the development of nutritional anemia. The increased availability of food, better resource utilization, and improved habitats quality can support a more balanced nutritional profile (Bhadra & Deb, 2020).The above-mentioned iron and vitamin B12 are very difficult to obtain from the plant-based diet and are generally poorly absorbable. Various diseases of the digestive tract can also play a role, which reduce the ability to absorb these substances. They are primarily found in animal products, which are not easily available to the populations in developing countries.Microalgae and cyanobacteria (MaC) are known as sources of proteins, amino acids, fatty acids, vitamins, minerals, and pigment (Tokuşoglu & üUnal, 2003). MaC also contain natural antioxidants which are used in the pharmaceutical and food industries to prevent oxidation and peroxidation processes (Seghiri, Kharbach, & Essamri, 2019). The protein content of MaC ranges from 50 to 70% of its dry weight (including many amino acids, particularly essential amino acids such as leucine, valine, and isoleucine) (Janssen, Wijffels, & Barbosa, 2022). Microalgae and cyanobacteria biomasses can thus be incorporated as functional ingredients in nutraceutical products due to their high potential to positively influence human health and have the potential to meet humanity's needs in terms of more sustainable food sources (particularly proteins) in the coming decades (Matos, Novelli, & Tribuzi, 2022). It thus is important to ensure that a suitable combination of different types of MaC are designed with an ideal content including all the necessary substances and in an amount that will be positively accepted by the human body.This research aims at identifying additional sources of vitamin B12, iron, amino acids, and proteins in desired amounts that can be combined to create a product capable of reducing the prevalence of anemia and other forms of malnutrition worldwide. For this purpose, two organisms approved by the European Union and the United States Food and Drug Administration for consumption and use in the food industry were selected, i.e., Arthrospira (Limnospira) maxima and the green microalgae, Chlorella vulgaris (Sharp, 2016).
Which vitamin is not associated with a deficiency disease?Multiple choice question.CholineThiaminNiacin
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