Which of the following is NOT one of the three desirable characteristics specifically expected of a suspension as a dosage form? A. the velocity of falling particles is greater for large and dense particles than for small, less dense particles B. particle size of the dispersed phase (suspensoid) should remain uniform and not form aggregates C. the suspension should pour readily and evenly from the container D. the dispersed phase should settle slowly and be easily resuspended with gentle shaking
Question
Which of the following is NOT one of the three desirable characteristics specifically expected of a suspension as a dosage form?
A. the velocity of falling particles is greater for large and dense particles than for small, less dense particles
B. particle size of the dispersed phase (suspensoid) should remain uniform and not form aggregates
C. the suspension should pour readily and evenly from the container
D. the dispersed phase should settle slowly and be easily resuspended with gentle shaking
Solution
The answer is A. The velocity of falling particles is greater for large and dense particles than for small, less dense particles. This is not a desirable characteristic of a suspension as a dosage form. In fact, it's the opposite. In a well-formulated suspension, the particles should be of uniform size and density to prevent rapid settling and to ensure that the drug is evenly distributed throughout the suspension. This allows for accurate dosing and better patient compliance. The other options (B, C, and D) are indeed desirable characteristics of a suspension.
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