During an inflammatory response, which is the correct order forcellular events?A) Filtration of monocytes from blood, increased production ofneutrophils, activation of tissue macrophages, infiltration ofneutrophils from the bloodB) Activation of tissue macrophages, infiltration of neutrophilsfrom the blood, infiltration of monocytes from blood, increasedproduction of neutrophilsC) Increased production of neutrophils, activation of tissuemacrophages, infiltration of neutrophils from the blood,infiltration of monocytes from bloodD) Infiltration of neutrophils from the blood, activation of tissuemacrophages, infiltration of monocytes from blood, increasedproduction of neutrophils
Question
During an inflammatory response, which is the correct order forcellular events?A) Filtration of monocytes from blood, increased production ofneutrophils, activation of tissue macrophages, infiltration ofneutrophils from the bloodB) Activation of tissue macrophages, infiltration of neutrophilsfrom the blood, infiltration of monocytes from blood, increasedproduction of neutrophilsC) Increased production of neutrophils, activation of tissuemacrophages, infiltration of neutrophils from the blood,infiltration of monocytes from bloodD) Infiltration of neutrophils from the blood, activation of tissuemacrophages, infiltration of monocytes from blood, increasedproduction of neutrophils
Solution
The correct order for cellular events during an inflammatory response is:
B) Activation of tissue macrophages, infiltration of neutrophils from the blood, infiltration of monocytes from blood, increased production of neutrophils
Here's why:
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Activation of tissue macrophages: The inflammatory response begins when tissue macrophages are activated by pathogens or damaged cells. These macrophages release cytokines and chemokines that initiate the inflammatory response.
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Infiltration of neutrophils from the blood: The cytokines and chemokines released by the activated macrophages attract neutrophils, a type of white blood cell, from the bloodstream to the site of inflammation.
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Infiltration of monocytes from blood: After the neutrophils, monocytes (another type of white blood cell) are attracted to the site of inflammation. They leave the bloodstream and enter the tissue where they differentiate into macrophages.
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Increased production of neutrophils: As the inflammatory response continues, the body increases the production of neutrophils in the bone marrow to replace those being used at the site of inflammation. This is often a later response to ensure a sustained supply of these cells if the inflammation continues.
Similar Questions
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