Regarding the major histocompatibility class II (MHC II) molecule, which of the following statements is TRUE?Select one alternative:Antigenic peptides are anchored along the peptide binding groove in MHC II.Each MHC II molecule can present only one specific (cognate) antigen.MHC II molecules present endogenous antigens, from within the cell.MHC II is expressed on all nucleated cells in the body.
Question
Regarding the major histocompatibility class II (MHC II) molecule, which of the following statements is TRUE?Select one alternative:Antigenic peptides are anchored along the peptide binding groove in MHC II.Each MHC II molecule can present only one specific (cognate) antigen.MHC II molecules present endogenous antigens, from within the cell.MHC II is expressed on all nucleated cells in the body.
Solution
The correct statement is: "Antigenic peptides are anchored along the peptide binding groove in MHC II."
Explanation:
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MHC II molecules bind to antigenic peptides, which are then presented on the cell surface. These peptides are anchored along the peptide-binding groove of the MHC II molecule.
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Each MHC II molecule can present a variety of different antigens, not just one specific (cognate) antigen.
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MHC II molecules present exogenous antigens, which are derived from outside the cell. This is in contrast to MHC I molecules, which present endogenous antigens from within the cell.
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MHC II is not expressed on all nucleated cells in the body. It is primarily expressed on antigen-presenting cells (APCs) such as macrophages, dendritic cells, and B cells.
Similar Questions
The major histocompatibility complex type I (MHC I) __________.ANSWERinteracts with CD4 on T helper cellsis found only on antigen-presenting cellsis found on all body cells except red blood cellspresents extracellular antigens
Describe how do Class II Major Histocompatibility Complex receptors (MHC-II receptors) work.
MHC class I is BEST DESCRIBED by which statement?Select one alternative:It presents viral peptides to CD8 T cells.It presents foreign peptides to CD4 T cells.It captures foreign peptides from extracellular pathogens.It is only expressed on specialised antigen presenting cells.
Which of the following is NOT considered as professional antigen presenting cells expressing MHC Class II?Thyroid epithelial cellsB cellsMacrophagesDendritic cells
Which of the following statements is true?Macrophages do not express any MHC molecules on their surface.Macrophages express both class I and class II MHC molecules.Macrophages only express class I MHC molecules.Macrophages only express class II MHC molecules.
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