Liver dysfunction will decrease production of each of the following proteins EXCEPT:Question 8Select one:a.Thrombopoietinb.Plasminogen activatorc.Factor Vd.Factor VIIe.Albumin
Question
Liver dysfunction will decrease production of each of the following proteins EXCEPT:Question 8Select one:a.Thrombopoietinb.Plasminogen activatorc.Factor Vd.Factor VIIe.Albumin
Solution
The liver is responsible for the production of many proteins, including thrombopoietin, plasminogen activator, Factor V, Factor VII, and albumin.
a. Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the production of platelets by the bone marrow. If the liver is dysfunctional, the production of thrombopoietin may decrease.
b. Plasminogen activator is a group of enzymes that catalyze the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. The liver is one of the organs that produce plasminogen activator, so liver dysfunction can lead to a decrease in its production.
c. Factor V is a protein of the coagulation system, usually present in an inactive form, which is converted to the active form by thrombin. It is produced by the liver and any dysfunction of the liver can affect its production.
d. Factor VII is one of the proteins that cause blood to clot in the coagulation cascade. It is produced in the liver and can be decreased in liver dysfunction.
e. Albumin is a protein made by the liver that keeps fluid from leaking out of blood vessels, nourishes tissues, and transports hormones, vitamins, drugs, and substances like calcium throughout the body. Liver dysfunction can lead to a decrease in albumin production.
Therefore, liver dysfunction can decrease the production of all the proteins listed above. The question seems to be incorrect as it states that liver dysfunction will not decrease the production of one of these proteins, which is not accurate.
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