149. Which of the following liver cell types will be most likely be affected in case of fatty changes and fibrotic cirrhosis?a.Hepatocytesb.Ito cellsc.Kupffer cellsd.Pit cells
Question
- Which of the following liver cell types will be most likely be affected in case of fatty changes and fibrotic cirrhosis?a.Hepatocytesb.Ito cellsc.Kupffer cellsd.Pit cells
Solution
The liver cell types most likely to be affected in the case of fatty changes and fibrotic cirrhosis are:
a. Hepatocytes b. Ito cells
Hepatocytes are the main cell type in the liver and perform most of the liver's functions. They are responsible for the production of bile, which is necessary for digestion. In the case of fatty changes, these cells accumulate fat, which can lead to liver damage and eventually cirrhosis.
Ito cells, also known as hepatic stellate cells, are responsible for the production of extracellular matrix proteins, including collagen. In the case of fibrotic cirrhosis, these cells become activated and produce excessive amounts of collagen, leading to the formation of fibrous scar tissue.
Therefore, both hepatocytes and Ito cells are likely to be affected in the case of fatty changes and fibrotic cirrhosis.
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