Which of the following is inhibited by cholinergic transmission? A)G cell B)ECL cell C)Parietal cell D)Gastric proton pump

The answer is D) Gastric proton pump.

Here's the step-by-step explanation:

1. Cholinergic transmission refers to the process where acetylcholine (ACh) is the primary neurotransmitter. It is involved in several functions including muscle stimulation, memory formation, and learning.

2. In the context of gastric physiology, cholinergic transmission plays a role in the regulation of acid secretion.

3. G cells, ECL cells, and parietal cells are all part of the gastric system. G cells produce gastrin, a hormone that stimulates the gastric acid secretion. ECL cells produce histamine, which also stimulates acid secretion. Parietal cells are the ones that actually secrete the gastric acid.

4. The gastric proton pump, also known as the H+/K+ ATPase, is the final step in the secretion of gastric acid in the stomach. It is located in the parietal cells.

5. Cholinergic transmission inhibits the gastric proton pump. This is because acetylcholine, the neurotransmitter involved in cholinergic transmission, has an inhibitory effect on the proton pump. This means that when acetylcholine is present, the activity of the proton pump is reduced, leading to a decrease in gastric acid secretion.

So, the gastric proton pump is inhibited by cholinergic transmission.