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An 84-year-old woman is brought to the emergency department after she was found abandoned in her home after a severe hurricane 4 days previously. The patient suffers from dementia and is wheelchair bound because of a healing hip fracture but has no other significant medical problems. On examination the patient is alert but disoriented, weight 60 kg, BP 100/60, HR 100, respiratory rate (RR) 16. You note poor skin turgor but no other acute abnormalities other than related to her hip fracture. Laboratory values are as follows:Na+ 156 mEq/LK+ 3.8 mEq/LBUN 38 mg/dLCreatinine 1.3 mg/dL Which of the following would be the most appropriate orders for the management of this patient's fluid and electrolyte status?Ask StudybuddyGroup of answer choices2-L bolus of 0.9% saline followed by 0.9% saline at 100 mL/hourD5W at 100 mL/hour with 60 mg furosemide IV × 1.3% saline at 100 mL/hour2-L bolus of D5W (5% dextrose solution in water) followed by D5W at 100 mL/hour0.45% saline at 150 mL/hour

Question

An 84-year-old woman is brought to the emergency department after she was found abandoned in her home after a severe hurricane 4 days previously. The patient suffers from dementia and is wheelchair bound because of a healing hip fracture but has no other significant medical problems. On examination the patient is alert but disoriented, weight 60 kg, BP 100/60, HR 100, respiratory rate (RR) 16. You note poor skin turgor but no other acute abnormalities other than related to her hip fracture. Laboratory values are as follows:Na+ 156 mEq/LK+ 3.8 mEq/LBUN 38 mg/dLCreatinine 1.3 mg/dL Which of the following would be the most appropriate orders for the management of this patient's fluid and electrolyte status?Ask StudybuddyGroup of answer choices2-L bolus of 0.9% saline followed by 0.9% saline at 100 mL/hourD5W at 100 mL/hour with 60 mg furosemide IV × 1.3% saline at 100 mL/hour2-L bolus of D5W (5% dextrose solution in water) followed by D5W at 100 mL/hour0.45% saline at 150 mL/hour

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Solution

This patient's presentation is consistent with severe hypernatremia (Na+ 156 mEq/L; normal range 135-145 mEq/L), likely due to dehydration from inadequate fluid intake and increased insensible losses. Hypernatremia develops when there is a loss of water in relation to body's sodium stores, which can occur from inadequate fluid intake, excessive water losses, or a combination of both. Symptoms of hypernatremia are primarily neurologic and this patient's altered mental status may be attributed to it.

The treatment of hypernatremia involves correcting the water deficit and addressing the underlying cause. Rapid correction of hypernatremia can lead to cerebral edema and neurologic damage, so the correction rate should not exceed 10 mEq/L in the first 24 hours and 18 mEq/L in the first 48 hours.

Given this patient's severe dehydration and hypernatremia, the most appropriate initial management would be to administer 0.9% saline (normal saline), which is isotonic, to correct the volume status and then switch to a hypotonic fluid such as 0.45% saline or D5W to correct the free water deficit. Therefore, the correct answer would be "2-L bolus of 0.9% saline followed by 0.9% saline at 100 mL/hour".

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