In a sample of 1,000 individuals, you discover that a particular single-nucleotide polymorphism (SNP) is present in 300 individuals. Calculate the polymorphism frequency of this SNP.
Question
In a sample of 1,000 individuals, you discover that a particular single-nucleotide polymorphism (SNP) is present in 300 individuals. Calculate the polymorphism frequency of this SNP.
Solution
To calculate the frequency of the single-nucleotide polymorphism (SNP), you need to divide the number of individuals with the SNP by the total number of individuals in the sample.
Here are the steps:
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Identify the number of individuals with the SNP. In this case, it's 300.
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Identify the total number of individuals in the sample. In this case, it's 1,000.
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Divide the number of individuals with the SNP by the total number of individuals.
So, the calculation would be: 300 / 1,000 = 0.3
Therefore, the frequency of the SNP in this sample is 0.3 or 30%.
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