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Acetylcholine is released into the synaptic cleft under the influence of

Question

Acetylcholine is released into the synaptic cleft under the influence of

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Solution

Acetylcholine is released into the synaptic cleft under the influence of an action potential. Here are the steps:

  1. An action potential (electrical signal) travels down the axon of the neuron towards the axon terminal.

  2. When the action potential reaches the axon terminal, it causes voltage-gated calcium channels to open.

  3. Calcium ions flow into the neuron, causing vesicles filled with acetylcholine to move towards and fuse with the presynaptic membrane.

  4. The acetylcholine is then released into the synaptic cleft via exocytosis.

  5. The acetylcholine molecules cross the synaptic cleft and bind to receptors on the postsynaptic neuron, transmitting the signal.

  6. The acetylcholine in the synaptic cleft is then broken down by an enzyme called acetylcholinesterase, and the choline is taken back up into the presynaptic neuron to be reused.

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