Which of the following is an absolute contraindication to fibrinolytic therapy?Prior intracranial hemorrhageHistory of poorly controlled hypertensionPregnancyMenses
Question
Which of the following is an absolute contraindication to fibrinolytic therapy?Prior intracranial hemorrhageHistory of poorly controlled hypertensionPregnancyMenses
Solution
The absolute contraindication to fibrinolytic therapy among the options provided is Prior intracranial hemorrhage.
Here's why:
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Prior intracranial hemorrhage: This is an absolute contraindication because fibrinolytic therapy can increase the risk of a recurrent bleed. Fibrinolytics work by breaking down clots, which can lead to bleeding. If a patient has had a previous intracranial hemorrhage, this risk is significantly increased.
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History of poorly controlled hypertension: While this is a relative contraindication, meaning the risks and benefits must be weighed, it is not an absolute contraindication.
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Pregnancy: This is generally a relative contraindication as well. The concern is primarily for the risk of bleeding during delivery, but this risk must be weighed against the potential benefits of therapy.
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Menses: This is not a contraindication. While women on their period may have a slightly increased risk of bleeding, it is not significant enough to contraindicate therapy.
So, the only absolute contraindication in this list is a prior intracranial hemorrhage.
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