Which one of the following drugs is NOT an immune checkpoint inhibitor?(A) Ipilimumab(B) Pembrolizumab(C) Nivolumab(D) Trastuzumab
Question
Which one of the following drugs is NOT an immune checkpoint inhibitor?(A) Ipilimumab(B) Pembrolizumab(C) Nivolumab(D) Trastuzumab
Solution
The drug that is NOT an immune checkpoint inhibitor among the options provided is (D) Trastuzumab.
Here's why:
(A) Ipilimumab is an immune checkpoint inhibitor that targets CTLA-4, a protein receptor that downregulates the immune system.
(B) Pembrolizumab is an immune checkpoint inhibitor that targets PD-1, a protein on the surface of certain immune cells (like T cells) that helps keep the body's immune responses in check.
(C) Nivolumab is also an immune checkpoint inhibitor that targets PD-1.
(D) Trastuzumab, however, is not an immune checkpoint inhibitor. It is a monoclonal antibody that interferes with the HER2/neu receptor. Its main use is to treat certain breast cancers.
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