Which of the following membrane receptors act as dimers that result in protein phosphorylation reactions following ligand binding?Group of answer choicesLigand gated ion channelsAdhesion receptorsReceptor tyrosine kinasesG protein-coupled receptors
Question
Which of the following membrane receptors act as dimers that result in protein phosphorylation reactions following ligand binding?Group of answer choicesLigand gated ion channelsAdhesion receptorsReceptor tyrosine kinasesG protein-coupled receptors
Solution 1
The membrane receptors that act as dimers and result in protein phosphorylation reactions following ligand binding are Receptor tyrosine kinases.
Here's a step-by-step explanation:
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Receptor tyrosine kinases (RTKs) are a class of cell surface receptors that respond to the binding of extracellular molecules, known as ligands.
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When a ligand binds to an RTK, it causes the receptor to form a dimer (a complex of two RTK molecules). This is known as dimerization.
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Dimerization activates the RTK's kinase activity. This means the RTK can add
Solution 2
The membrane receptors that act as dimers and result in protein phosphorylation reactions following ligand binding are Receptor tyrosine kinases.
Here's a step-by-step explanation:
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Receptor tyrosine kinases (RTKs) are a class of cell surface receptors that respond to the binding of extracellular molecules, known as ligands.
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When a ligand binds to an RTK, it causes the receptor to form a dimer (a complex of two RTK molecules). This is known as dimerization.
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Dimerization activates the RTK's kinase activity. This means the RTK can add a phosphate group to tyrosine residues on certain proteins - a process known as phosphorylation.
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This phosphorylation can trigger a cascade of events inside the cell, leading to changes in gene expression, cell growth, or cell differentiation.
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The other options - ligand-gated ion channels, adhesion receptors, and G protein-coupled receptors - also play important roles in cell signaling, but they do not act as dimers that result in protein phosphorylation reactions following ligand binding.
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