Q28. Which of the following comments about aldosterone is correct?a) Aldosterone is secreted from macula densa cellsb) Aldosterone stimulates reabsorption in the ascending loop of Henlec) Aldosterone directly stimulates the reabsorption of sodiumd) Aldosterone directly stimulates the reabsorption of wate
Question
Q28. Which of the following comments about aldosterone is correct?a) Aldosterone is secreted from macula densa cellsb) Aldosterone stimulates reabsorption in the ascending loop of Henlec) Aldosterone directly stimulates the reabsorption of sodiumd) Aldosterone directly stimulates the reabsorption of wate
Solution
The correct answer is c) Aldosterone directly stimulates the reabsorption of sodium.
Here's why:
a) Aldosterone is not secreted from macula densa cells. It is secreted from the adrenal cortex, specifically the zona glomerulosa.
b) Aldosterone does not stimulate reabsorption in the ascending loop of Henle. It primarily acts on the cells of the distal tubules and collecting ducts in the kidneys.
c) Aldosterone directly stimulates the reabsorption of sodium. This is correct. Aldosterone increases the reabsorption of sodium ions from the renal tubular fluid in the kidneys back into the blood, which indirectly leads to water retention and increased blood volume and pressure.
d) Aldosterone does not directly stimulate the reabsorption of water. It indirectly influences water reabsorption by increasing sodium reabsorption, which creates an osmotic gradient that drives water reabsorption. However, the direct reabsorption of water is primarily controlled by antidiuretic hormone (ADH), not aldosterone.
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