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presence of crystals in a mannitol injection indicates that the product? a. has settled during transportation b. was formulated using sterile saline c. contains impurities and should be discarded d. was exposed to excessive cold

Question

presence of crystals in a mannitol injection indicates that the product? a. has settled during transportation b. was formulated using sterile saline c. contains impurities and should be discarded d. was exposed to excessive cold

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Solution

The presence of crystals in a mannitol injection indicates that the product was exposed to excessive cold. So, the correct answer is d. "was exposed to excessive cold". Mannitol can crystallize at low temperatures. If this happens, the product should be warmed until the crystals dissolve and then cooled to room temperature before use.

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