Although healthcare providers may prescribe niacin supplements for patients who cannot tolerate statins, the treatment can have several unwanted side effects, such as flushing of the skin and liver damage.Group startsTrue or FalseTrue, unselectedFalse, unselected

Statins may be prescribed to anyone at risk of cardiovascular disease. They work by:Breaking down cholesterolIncreasing the production of cholesterol by the liverReducing the production of cholesterol by the liverSuppressing the immune system

Statins are widely used to reduce blood cholesterol levels by slowing down the rate of fatty material deposits. A reported side effect of taking statins is that they also reduce blood pressure. A sample of patients with high blood cholesterol was offered statins as treatment. Their blood pressure was taken before treatment started and at weekly intervals.Table 2 shows the percentage of patients with lower blood pressure several weeks after starting treatment. 440 patients took statins and 300 patients took a placebo (not statins).Explain the conclusion that statins reduce blood pressure.

Statins are medicines which reduce blood cholesterol levels. Different medicines, called ACEinhibitors, can reduce blood pressure.Suggest why statins and ACE inhibitors are only given to individuals with high cholesterol orblood pressure........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ [2](c) Scientists wanted to know if taking statins and ACE inhibitors would reduce the risk ofdeveloping CVD in people with average blood pressure. The scientists recorded the bloodpressure and age of every person who took part in the study.(i) Suggest one more piece of information that would be useful to know about the peoplein the study....................................................................................................................................... [1](ii) The people taking part in the study were put in two groups. One group was given aplacebo. The other group was given statins and ACE inhibitors.Explain why it was ethical to use a placebo in this study........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ [2]

In the United States, people at risk for niacin deficiency include those withMultiple select question.

Currently, niacin-containing medications are _____ recommended for most individuals with cardiovascular disease.Multiple choice question.frequentlyno longer