Although acetylsalicylic acid (aspirin) is a well-known and widely used analgesic and anti-inflammatory agent, copper(II) acetylsalicylate, a copper complex formed from aspirin and copper, has also been found to exhibit some distinctive and potentially beneficial pharmacological properties. Formation of copper(II) acetylsalicylate is achieved by dissolving an aspirin salt in water (Reaction 1) and then introducing Cu2+ ions which bind to the conjugate base of aspirin, acetylsalicylate (C9H7O4−), as outlined in Reaction 2.NaC9H7O4(s) ⇄ Na+(aq) + C9H7O4−(aq)Reaction 14 NaC9H7O4(aq) + 2 CuSO4(aq) → Cu2(C9H7O4)4(s) + 2 Na2SO4(aq)Reaction 2Using Reaction 2, a researcher synthesized a sample of copper(II) acetylsalicylate for analysis. A small volume of 0.50 M aqueous copper(II) sulfate (molar mass = 159.6) was mixed into 100 mL of filtered, saturated aqueous sodium acetylsalicylate (molar mass = 202.2) at room temperature and slowly stirred. Formation of copper(II) acetylsalicylate (molar mass = 843.7) was immediately observed as a bright blue precipitate. The precipitate was then isolated by filtration and dried, affording the product complex in high yield.Adapted from: Seguel GV, Rivas BL, Contreras JG. Synthesis and characterization of copper complexes: interaction of metalliccarboxylates with 1,3-thiazole ligand. Journal of the Chilean Chemical Society. 1970; 58(4):1967. Question 29In Reaction 2, just prior to precipitation, what is the ratio of the concentration of copper(II) acetylsalicylate to the concentration of sodium sulfate?A.1/4B.1/2C.2/2D.2/1
Question
Although acetylsalicylic acid (aspirin) is a well-known and widely used analgesic and anti-inflammatory agent, copper(II) acetylsalicylate, a copper complex formed from aspirin and copper, has also been found to exhibit some distinctive and potentially beneficial pharmacological properties. Formation of copper(II) acetylsalicylate is achieved by dissolving an aspirin salt in water (Reaction 1) and then introducing Cu2+ ions which bind to the conjugate base of aspirin, acetylsalicylate (C9H7O4−), as outlined in Reaction 2.NaC9H7O4(s) ⇄ Na+(aq) + C9H7O4−(aq)Reaction 14 NaC9H7O4(aq) + 2 CuSO4(aq) → Cu2(C9H7O4)4(s) + 2 Na2SO4(aq)Reaction 2Using Reaction 2, a researcher synthesized a sample of copper(II) acetylsalicylate for analysis. A small volume of 0.50 M aqueous copper(II) sulfate (molar mass = 159.6) was mixed into 100 mL of filtered, saturated aqueous sodium acetylsalicylate (molar mass = 202.2) at room temperature and slowly stirred. Formation of copper(II) acetylsalicylate (molar mass = 843.7) was immediately observed as a bright blue precipitate. The precipitate was then isolated by filtration and dried, affording the product complex in high yield.Adapted from: Seguel GV, Rivas BL, Contreras JG. Synthesis and characterization of copper complexes: interaction of metalliccarboxylates with 1,3-thiazole ligand. Journal of the Chilean Chemical Society. 1970; 58(4):1967. Question 29In Reaction 2, just prior to precipitation, what is the ratio of the concentration of copper(II) acetylsalicylate to the concentration of sodium sulfate?A.1/4B.1/2C.2/2D.2/1
Solution
The ratio of the concentration of copper(II) acetylsalicylate to the concentration of sodium sulfate can be determined by looking at the stoichiometry of Reaction 2.
In Reaction 2, the balanced chemical equation is:
4 NaC9H7O4(aq) + 2 CuSO4(aq) → Cu2(C9H7O4)4(s) + 2 Na2SO4(aq)
This equation tells us that for every 1 molecule of Cu2(C9H7O4)4 that forms, 2 molecules of Na2SO4 are also formed. Therefore, the ratio of the concentration of copper(II) acetylsalicylate to the concentration of sodium sulfate is 1:2.
So, the correct answer is B. 1/2.
Similar Questions
Aspirin (acetylsalicylic acid) is a well-known pain reliever and anti-inflammatory drug. However, it can cause stomach irritation in some individuals. Acetaminophen, another common pain reliever, is gentler on the stomach but lacks the anti-inflammatory properties of aspirin. Here's a challenge that combines organic chemistry concepts!The Task: Develop a two-step synthesis plan to convert aspirin (acetylsalicylic acid) into acetaminophen (N-acetyl-p-aminophenol).Clues and Considerations:Aspirin has an ester functional group (carbonyl bonded to an oxygen and then an alkyl group).Acetaminophen has an amide functional group (carbonyl bonded to a nitrogen and then a carbon).Both molecules share a similar aromatic ring structure with a hydroxyl group (-OH) attached.Possible Steps:Step 1: What kind of reaction could be used to break the ester bond in aspirin?Step 2: How can the resulting intermediate be transformed into an amide group to yield acetaminophen?Bonus Challenge:Identify the reagents required for each step of your proposed synthesis.
Aspirin (acetylsalicylic acid) was synthesised in the following experiment:8.25 g of salicylic acid (Msalicylic acid = 138.13 g mol–1) was reacted with 10.0 g of ethanoic anhydride (Manhydride = 102.10 g mol–1) in the presence of a concentrated sulfuric acid catalyst. 8.55 g of a white solid was collected at the end of the reaction.salicylic acid + ethanoic anhydride → acetylsalicylic acid + ethanoic acidCalculate the percentage yield of aspirin. State your answer to three significant figures. Maspirin = 180.17 g mol–1.
Aspirin is known as :acetyl salicylic acidphenyl salicylateacetyl salicylatemethyl salicylic acid
Oh no! A chemist has bumped their head into a doorway in the lab and has developed a mild headache. Annoyed by this headache, they decide to take two aspirin tablets to relieve the pain. Aspirin is also known as acetylsalicylic acid (C9H8O4), which is a weak monoprotic acid with a pKa of 3.5. Each aspirin tablet contains 500 mg of aspirin. The two tablets are dissolved into 390 mL of water in a glass - to two decimal places, what is the pH of this solution?
aspirin uses in relation to cardiovascular disease
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