There is a strong connection between drug use and __________.

There is a strong connection between drug use and addiction.

1. Identify the key terms: The key terms in the question are "drug use" and the blank space that needs to be filled.
2. Understand the context: Drug use often leads to various consequences, one of the most significant being addiction.
3. Fill in the blank: Based on the context, the word "addiction" fits well as it is a common and serious consequence of drug use.
4. Formulate the complete sentence: "There is a strong connection between drug use and addiction."

Thus, the completed sentence is: "There is a strong connection between drug use and addiction."