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what is the function of the c-reactive protein?

Question

what is the function of the c-reactive protein?

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C-reactive protein (CRP) is a substance produced by the liver in response to inflammation. The level of CRP rises when there is inflammation throughout the body. It is one of a group of proteins called acute phase reactants that go up in response to inflammation.

The main functions of C-reactive protein are:

  1. Binds to Phosphocholine: CRP binds to phosphocholine expressed on the surface of dead or dying cells and some types of bacteria. This helps the immune system to recognize and remove these cells and bacteria.

  2. Activates Complement System: CRP also binds to the complement system, a group of proteins that are part of the immune system. This binding activates the system, helping to kill bacteria and other foreign cells.

  3. Promotes Phagocytosis: By binding to dead cells and bacteria, CRP promotes their removal by phagocytosis. This is a process where certain cells engulf and destroy these unwanted cells.

  4. Indicator of Inflammation: Doctors often use CRP levels as a marker of inflammation or infection in the body. High levels of CRP can indicate a higher risk of conditions like heart disease.

  5. Role in Atherosclerosis: Recent research suggests that CRP may play a direct role in the process of atherosclerosis, where fatty deposits build up in the arteries. However, this role is not yet fully understood.

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Similar Questions

Describe the function of the immune system.

C - Reactive Protein (CRP)InvestigationC - Reactive Protein (CRP)Result: 39.34Unitsmg/LBio. Ref. Interval< 5• Sample Type : Serum.• Method : Turbidimetric.Clinical Significance :• C-Reactive Protein (CRP) is the most sensitive acute phase reactant for inflammation. The levels increase dramatically (100 fold or more) aftersevere trauma, bacterial infection, surgery and neoplastic proliferation. This assay is useful in detecting systemic inflammatory process andinfection. It assesses response to antibiotic treatment and differentiates between active and inactive disease forms with concurrent infection .Disclaimer :• The above result relate only to the specimens received and tested in laboratory and should be always correlate with clinical findings and otherlaboratory markers.• Improper specimen collection, handling, storage and transportation may result in false negative/Positive results.Kindly Correlate Clinically.--End Of Report--

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