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Which of the following parameters is used to indicate the ability of a drug to produce the desired therapeutic effect relative to a toxic effect? * (a) Potency (B) Intrinsic activity (C) Therapeutic Index (D) Efficacy (e) Bioavailability

Question

Which of the following parameters is used to indicate the ability of a drug to produce the desired therapeutic effect relative to a toxic effect? * (a) Potency (B) Intrinsic activity (C) Therapeutic Index (D) Efficacy (e) Bioavailability

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Solution

The correct answer is (C) Therapeutic Index. The therapeutic index of a drug is a measure of the drug's safety. It is calculated as the ratio of the dose that produces toxicity to the dose that produces a clinically desired or effective response in a population of individuals. A drug with a high therapeutic index is safer than a drug with a low therapeutic index.

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