Anti-emetic of choice for post-chemotherapy induced vomiting
Question
Anti-emetic of choice for post-chemotherapy induced vomiting
Solution
The anti-emetic of choice for post-chemotherapy induced vomiting is usually a combination of drugs due to the severity of the nausea and vomiting that can occur.
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Serotonin (5-HT3) receptor antagonists: These are often the first line of defense. Drugs in this class include ondansetron (Zofran), granisetron (Kytril), and palonosetron (Aloxi).
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Neurokinin 1 (NK1) receptor antagonists: These are often used in combination with 5-HT3 antagonists and corticosteroids. Aprepitant (Emend) is a drug in this class.
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Corticosteroids: Dexamethasone is often used in combination with other anti-emetics.
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Other drugs: Metoclopramide (Reglan) and olanzapine (Zyprexa) can also be used.
The choice of anti-emetic can depend on the type of chemotherapy, the patient's other medications, and the patient's personal response to anti-emetic drugs. It's important to note that while these medications can significantly reduce nausea and vomiting, they may not eliminate these symptoms completely.
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