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What direction does the newly synthesized DNA strand form

Question

What direction does the newly synthesized DNA strand form

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Solution

The newly synthesized DNA strand forms in the 5' to 3' direction. Here are the steps explaining why:

  1. DNA replication begins at specific points in the genome called origins of replication.

  2. The enzyme DNA helicase unwinds the double helix at the origin, creating a replication fork.

  3. DNA polymerase, the enzyme that synthesizes the new DNA strand, can only add nucleotides to the 3' end of a DNA strand.

  4. Therefore, the new DNA strand is synthesized in the 5' to 3' direction, which is opposite to the direction in which the template strand is read (3' to 5').

  5. This process continues until the entire molecule is copied. The end result is two DNA molecules, each consisting of one original and one newly synthesized strand.

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