Which of the following statements is/are correct in relation to either Osteoarthritis (OA) or Rheumatoid Arthritis (RA)?W. An auto-immune reaction occurs in joints of individuals with RA, but not in joints of people with OA.X.  On the whole, joints are more inflamed in OA than in RA.Y.  Ankylosis (joint fusion) commonly occurs in RA, but is unlikely to occur in OA.Z.  Having osteoporosis increases the risk of developing RA, but not OA.Question 54Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct

Which of the following statements is/are correct in relation to rheumatoid arthritis (RA)?W. RA is a chronic inflammatory disease that principally affects joints.X. The concentrations (titres) of Rheumatoid Factor deposited in joints does not influence disease severity.Y. The pathogenesis of joint destruction in RA involves both Type III and Type IV hypersensitivity reactions.Z. Development of RA greatly depends on repetitive impulse loading.Question 50Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct

Which of the following statements is/are correct in relation to osteoarthritis (OA)?Question 57Select one:a.Repetitive impulse loading of joints has no bearing on the pathogenesis of OA.b.OA is a degenerative joint disease, which results in a loss of articular cartilage.c.Chondrocytes in articular cartilage produce osteophytes.d.In OA, a pannus develops at joint margins and destroys the articular cartilage.e.OA development is associated with Type III and Type IV hypersensitivity reactions.

Which of the following statements is/are correct in relation to osteoarthritis (OA)?W. Development of OA is strongly associated with articular cartilage degradation.X.  Osteophytes develop at joint margins due to stimulation of periosteal bone/cartilage formation.Y.  OA typically develops asymmetrically, and is present in most individuals over the age of 65.Z.  In OA, articular cartilage matrix loses proteoglycans and gains water; making the cartilage more susceptible to damage.Question 7Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct

Which of the following statements pertaining to rheumatoid nodules is correct?W. Rheumatoid nodules are found in most individuals who have rheumatoid arthritis.X.  Rheumatoid nodules are mostly located in internal organs such as the heart, lungs and liver.Y.  The joint disease will likely resolve in people who have rheumatoid nodules.Z.  An individual with rheumatoid nodules will likely have a very destructive joint disease.Question 43Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct

Which of the following diseases is/are correctly matched to its pathogenesis?W. Osteoarthritis - chronic inflammation and hypersensitivity reactionsX. Rickets - bones are poorly mineralized and soft.Y.  Rheumatoid Arthritis - asymmetrical development in joints of hands and feet.Z. Osteomalacia - bones are poorly mineralized and soft.Question 27Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct