In temporal summation, a single presynaptic neuron stimulates the creation of action potentials in a postsynaptic neuron when it
Question
In temporal summation, a single presynaptic neuron stimulates the creation of action potentials in a postsynaptic neuron when it
Solution
In temporal summation, a single presynaptic neuron stimulates the creation of action potentials in a postsynaptic neuron when it repeatedly fires in quick succession. Here's the step-by-step process:
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The presynaptic neuron releases neurotransmitters into the synaptic cleft (the space between the presynaptic and postsynaptic neuron) each time it fires an action potential.
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These neurotransmitters bind to receptors on the postsynaptic neuron, causing ion channels to open.
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If the presynaptic neuron fires again quickly enough, it will release more neurotransmitters before the effects of the first action potential have worn off.
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This causes an even greater influx of ions into the postsynaptic neuron, bringing it closer to its threshold potential.
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If the presynaptic neuron continues to fire at a high frequency, the postsynaptic neuron will reach its threshold potential and fire an action potential.
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This process is known as temporal summation because the postsynaptic neuron is summing the effects of the presynaptic neuron's action potentials over time. If the presynaptic neuron fires too slowly, the postsynaptic neuron will not reach its threshold potential and an action potential will not be generated.
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