Which structural change to lidocaine will increase its efficacy as an anesthetic?A.propyl amine groups instead of ethyl amine groups at the β positionB.1° β amineC.2° β amineD.Addition of a hydroxyl group to the aromatic ring

To increase the solubility of the anesthetic within the injection carrier solution, clinicians convert lidocaine to a salt by reacting it with:A.KOHB.Na2CO3C.HClD.LiCl

Lidocaine is a common local anesthetic used to relieve minor pain, itching, and burning. The molecule has 4 double bonds and 1 ring. How many hydrogen atoms would be in lidocaine's formula, C14H?N2O?Type your answer here (Enter a whole number only)

Amines constitute an important class of organiccompounds derived by replacing one or more hydrogenatoms of ammonia molecule by alkyl/aryl group(s). Innature, they occur among proteins, vitamins, alkaloidsand hormones. Synthetic examples include polymers,dyestuffs and drugs. Two biologically active compounds,namely adrenaline and ephedrine, both containingsecondary amino group, are used to increase bloodpressure. Novocain, a synthetic amino compound, isused as an anaesthetic in dentistry. Benadryl, a wellknown antihistaminic drug also contains tertiary aminogroup. Quaternary ammonium salts are used assurfactants. Diazonium salts are intermediates in thepreparation of a variety of aromatic compoundsincluding dyes. In this Unit, you will learn about aminesand diazonium salts

Lidocaine is a local anesthetic that is used during invasive procedures like surgery, needle punctures, or insertions of catheter or breathing tubes. The maximum dose of lidocaine is 4.5 mg/ kg body weight. What is the maximum volume of a 1% (m/v) lidocaine solution that can be injected into a Filipino patient (average weight of a Filipino man is 46 kg).

Lidocaine is injected into infected tissue with a pH of 6.5. At the injection site, one would expect:A.higher [R3N]/[R3NH+] ratioB.increased duration of actionC.slower onset of actionD.increased R3NH+ diffusion rate across the membrane