A patient found to have an abnormally low number of helper T cells in her blood contracts a bacterial infection. During the infection, which of the following is most likely NOT affected by the patient's low count of helper T cells?A.Expression of major histocompatibility complex proteins that present bacterial antigens on the membrane of infected host cellsB.Proliferation of B lymphocytes in response to the bacterial infectionC.Levels of circulating antibodies against the invading bacteriumD.Activation of apoptosis-inducing cytotoxic T cells
Question
A patient found to have an abnormally low number of helper T cells in her blood contracts a bacterial infection. During the infection, which of the following is most likely NOT affected by the patient's low count of helper T cells?A.Expression of major histocompatibility complex proteins that present bacterial antigens on the membrane of infected host cellsB.Proliferation of B lymphocytes in response to the bacterial infectionC.Levels of circulating antibodies against the invading bacteriumD.Activation of apoptosis-inducing cytotoxic T cells
Solution
The answer is A. Expression of major histocompatibility complex proteins that present bacterial antigens on the membrane of infected host cells.
Here's why:
A. The expression of major histocompatibility complex (MHC) proteins is not directly affected by the count of helper T cells. MHC proteins are expressed by all nucleated cells in the body and their expression is not dependent on the presence of helper T cells. They present antigens, including bacterial antigens, on the surface of infected cells, which can then be recognized by T cells.
B. The proliferation of B lymphocytes in response to a bacterial infection would likely be affected by a low count of helper T cells. Helper T cells play a crucial role in the activation and proliferation of B cells.
C. The levels of circulating antibodies against the invading bacterium would also likely be affected by a low count of helper T cells. Helper T cells stimulate B cells to produce antibodies.
D. The activation of apoptosis-inducing cytotoxic T cells would likely be affected by a low count of helper T cells. Helper T cells are necessary for the activation of cytotoxic T cells, which can induce apoptosis in infected cells.
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