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The end of a strand of nucleic acid that has a hydroxyl (OH) group on the number 3 carbon of the deoxyribose or ribose.1 point35'

Question

The end of a strand of nucleic acid that has a hydroxyl (OH) group on the number 3 carbon of the deoxyribose or ribose.1 point35'

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Solution

The end of a strand of nucleic acid that has a hydroxyl (OH) group on the number 3 carbon of the deoxyribose or ribose is referred to as the 3' end (pronounced "three prime end"). This is in contrast to the 5' end, which has a phosphate group attached to the number 5 carbon of the deoxyribose or ribose.

In DNA and RNA strands, the directionality is determined by these 3' and 5' ends, meaning that sequences are written and read in a 5' to 3' direction. This is important in processes such as DNA replication and transcription, where enzymes like DNA polymerase and RNA polymerase can only add nucleotides to the 3' end of the strand.

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