_catalyses the formation of phosphodiester bond between two deoxynucleotide residues of two DNA strands
Question
_catalyses the formation of phosphodiester bond between two deoxynucleotide residues of two DNA strands
Solution
The enzyme that catalyzes the formation of a phosphodiester bond between two deoxynucleotide residues of two DNA strands is DNA polymerase.
Here are the steps of how this process occurs:
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Initiation: The process begins with the unwinding of the double-stranded DNA by an enzyme called helicase. This creates a replication fork where DNA polymerase can begin its work.
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Primer Binding: A short RNA primer is synthesized by an enzyme called primase. This primer serves as a starting point for DNA polymerase.
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Elongation: DNA polymerase adds free nucleotides to the 3' end of the primer, forming a new strand of DNA. It does this by catalyzing the formation of a phosphodiester bond between the phosphate group of the incoming nucleotide and the 3' OH of the last nucleotide in the growing strand.
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Termination: Once the entire DNA molecule has been replicated, the process is terminated. The RNA primers are removed and replaced with DNA by another DNA polymerase, and the fragments of DNA are joined together by an enzyme called DNA ligase.
So, in summary, the enzyme that catalyzes the formation of a phosphodiester bond between two deoxynucleotide residues of two DNA strands is DNA polymerase.
Similar Questions
Which reaction in DNA replication is catalysed by DNA ligase?Group of answer choicesBase pairing of the template to the newly synthesised strandFormation of a phosphodiester linkage between two Okazaki fragmentsProof reading the template strand for errorsAddition of nucleotides to the lagging strand
The pairing of complementary bases in DNA (through hydrogen bonding) means that the information contained within each strand is redundant. Phosphodiester (intra-strand) bonds are stronger than hydrogen (inter-strand) bonds. The actual job of the phosphodiester bonds is where in DNA polymers connect the 5' carbon atom of one nucleotide to the 3' carbon atom of another nucleotide, while the hydrogen bonds stabilize DNA double helices across the helix axis but not in the direction of the axis.[19] This makes it possible to separate the strands from one another. The nucleotides on a single strand can therefore be used to reconstruct nucleotides on a newly synthesized partner strand.[20]
Strands of DNA are joined byMultiple Choicehydrogen bonds.covalent bonds.ionic bonds.phosphodiester bonds.
Which enzyme covalently links nucleotides together?
The enzyme DNA covalently links nucleotides to synthesize new DNA strands together during DNA replication.
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