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IVIVC for Modified Release dosage forms is a requirement of the USP. True False

Question

IVIVC for Modified Release dosage forms is a requirement of the USP. True False

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Solution

False. IVIVC (In Vitro In Vivo Correlation) for Modified Release dosage forms is not a requirement of the USP (United States Pharmacopeia). It is a tool that can be used to establish, validate, or verify the correlation between in vitro (laboratory) testing of a drug and its in vivo (body) response. However, it is not a mandatory requirement of the USP.

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Does IVIVC match this definition, This indicates the correlation between lab test results and drug product performance in a live patient.

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The dissolution of the drug from the dosage unit during the elapsed time is the USP test requirement for which of the following? A. Product uniformity and weight variation B. Drug release for extended release or delayed release dosage forms C. Microencapsulation and fluid bed processing D. Teeth, hair and eyeballs

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