There is a right shift of the O2 dissociation curve under all of the following conditions, exceptHigh pCO2High H+High temperatureHigh pH
Question
There is a right shift of the O2 dissociation curve under all of the following conditions, exceptHigh pCO2High H+High temperatureHigh pH
Solution
The O2 dissociation curve shifts to the right under conditions that promote the release of oxygen from hemoglobin, which include high pCO2, high H+ (low pH), and high temperature. These conditions are typically found in metabolically active tissues that require more oxygen.
However, high pH does not cause a right shift of the O2 dissociation curve. Instead, it causes a left shift. This is because a high pH (which is equivalent to low H+) promotes the binding of oxygen to hemoglobin, making it less likely to release oxygen. This is known as the Bohr effect. Therefore, the condition that does not cause a right shift of the O2 dissociation curve is high pH.
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