Manx cats have shortened tails due to the autosomal dominant allele M that affects spine formation. This allele is lethal in homozygotes. The autosomal recessive allele m leads to normal tail development. If two Manx cats are mated to each other, what is the fraction of offspring expected to have normal tail lengths?Multiple choice question.None of the offspring1/4All of the offspring1/21/3
Question
Manx cats have shortened tails due to the autosomal dominant allele M that affects spine formation. This allele is lethal in homozygotes. The autosomal recessive allele m leads to normal tail development. If two Manx cats are mated to each other, what is the fraction of offspring expected to have normal tail lengths?Multiple choice question.None of the offspring1/4All of the offspring1/21/3
Solution
The Manx cats have the autosomal dominant allele M, which is lethal in homozygotes. This means that the MM combination is not possible. The possible combinations are Mm (Manx cat) and mm (normal tail).
When two Manx cats (Mm) are mated, the possible combinations are:
- MM (which is not possible due to lethality)
- Mm (Manx cat)
- mM (Manx cat)
- mm (normal tail)
So, out of 4 possibilities, only 1 leads to a normal tail. Therefore, the fraction of offspring expected to have normal tail lengths is 1/4.
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