Which of the following statements about O2 transport in the blood is FALSE?Question 42Answera.Approximately 98% of O2 is transported around the body bound to haemoglobinb.Various local factors can alter the binding of haemoglobin to O2c.O2 is not particularly soluble in plasmad.Each haemoglobin molecule can bind up to four molecules of O2e.Haemoglobin saturation will significantly decrease with even small decreases in alveolar pO2
Question
Which of the following statements about O2 transport in the blood is FALSE?Question 42Answera.Approximately 98% of O2 is transported around the body bound to haemoglobinb.Various local factors can alter the binding of haemoglobin to O2c.O2 is not particularly soluble in plasmad.Each haemoglobin molecule can bind up to four molecules of O2e.Haemoglobin saturation will significantly decrease with even small decreases in alveolar pO2
Solution
The false statement is e. "Haemoglobin saturation will significantly decrease with even small decreases in alveolar pO2".
This is not true because the oxygen-hemoglobin dissociation curve is sigmoidal, not linear. This means that, within a certain range of partial pressures of oxygen (pO2), a decrease in alveolar pO2 will not significantly decrease hemoglobin saturation. Hemoglobin remains relatively saturated with oxygen even when the pO2 decreases, until a critical point is reached. This property allows hemoglobin to deliver oxygen to tissues even under conditions of lower oxygen availability.
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