A 100-mg dose of drug X is given every 8 hr until SS levels are reached. At SS, the AUC over the dosing interval is 32 (mg/L) x hr. What is the average concentration over that dosing interval? What is the estimated clearance for drug X?

An antibiotic QX has half-life of 6 hours and volume of distributionof 2L/Kg. what is the expected AUC after administration of a singleiv dose of 10mg/kg

The elimination rate constant of ibuprofen is 0.1155/hr and its volumeof distribution is 0.17 L/kg. What will be the dosing regimen requiredfor a 70-kg man to achieve an average plasma concentration of 50mg/L at steady state (bioavailability is 100%)a. 100 mg every 8 hoursb. 300 mg every 12 hoursc. 500 mg every 8 hoursd. 400 mg every 6 hours

Dosage and Concentration:

what is peak drug x level attained at steady state if 100mg is given intravenous injection every 6hrs. the patient ke=0.35/hr and Vd = 20L

for 6hrs the concentration is supposed to be 4.436mg/L, why are u getting 23.8mg/L